=> Bootstrap dependency digest>=20010302: found digest-20180917
=> Checksum SHA1 OK for pygtk-2.24.0.tar.bz2
=> Checksum RMD160 OK for pygtk-2.24.0.tar.bz2
=> Checksum SHA512 OK for pygtk-2.24.0.tar.bz2
mkdir: /tmp/pkgbuild/x11/py-gtk2: Permission denied
*** Error code 1

Stop.
make: stopped in /usr/pkgsrc/x11/py-gtk2